Nitroaspirin
Cat. No. :YN330188
CAS No. :175033-36-0
86-020-82000279
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order@ubiochem.com| Product Name: | Nitroaspirin |
| CAS NO.: | 175033-36-0 |
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| Molecular Weight: | 331.28 |
| Molecular Formula: | C₁₆H₁₃NO₇ |
| SMILES: | O=C(OC1=CC=CC(CO[N+]([O-])=O)=C1)C2=CC=CC=C2OC(C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Nitroaspirin (NCX 4016) is a nitric oxide (NO) donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin (NCX 4016) has antithrombotic and anti-platelet properties and acts as a direct and irreversible inhibitor ofCOX-1. Nitroaspirin (NCX 4016) causes significant induction of cell cycle arrest and apoptosisin Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins. |
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