TCS 21311
Cat. No. :YN310090
CAS No. :1260181-14-3
86-020-82000279
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order@ubiochem.com| Product Name: | TCS 21311 |
| CAS NO.: | 1260181-14-3 |
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| Molecular Weight: | 526.51 |
| Molecular Formula: | C₂₇H₂₅F₃N₄O₄ |
| SMILES: | O=C(C(C1=CC(N2CCN(C(C(C)(O)C)=O)CC2)=CC=C1C(F)(F)F)=C3C4=CNC5=C4C=CC=C5)NC3=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TCS 21311 (NIBR3049) is a potent, highly selectiveJAK3inhibitor with an IC50 of 8nM, it displays >100-fold selectivity over JAK1, JAK2 and TYK2. TCS 21311 (NIBR3049) inhibitsPKCα,PKCθ, and GSK3βwith IC50s of 13, 68, and 3nM, respectively. |
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