YN340125 EMI48

EMI48, the derivative of EMI1, displays greater potency toward mutantEGFRthan EMI1. EMI48 inhibitsEGFRtriple mutants.

YN340125 EMI48 34564-13-1

EMI48, the derivative of EMI1, displays greater potency toward mutantEGFRthan EMI1. EMI48 inhibitsEGFRtriple mutants.

YN310087 Bisindolylmaleimide X hydroc... 145317-11-9

Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selectiveprotein kinase C (PKC)inhibitor. Bisindolylmaleimide X hydrochloride is a potentcyclin-dependent kinase 2 (CDK2)antagonist with an IC50 of...

YN340203 TCS PIM-1 1 491871-58-0

TCS PIM-1 1 is a potent and selective inhibitor of ATP-competitive Pim-1 kianse with IC50 of 50 nM, shows good selectivity over Pim-2 and MEK1/MEK2 with IC50 > 20000 nM.

YN360705 Ca2+ channel agonist 1 1402821-24-2

Ca2+channel agonist 1 is an agonist ofN-type Ca2+channel and an inhibitor of CDK2, with EC50s of 14.23μM and 3.34μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction.

YN340279 Quercetagetin 90-18-6

Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated fromCitrus unshiu(C. unshiu) peel. Quercetagetin is a moderately potent and selective, cell-permeablepim-1kinase inhibitor (IC50, 0.34μM). Anti-inflammatory and...

YN310105 CGP60474 164658-13-3

CGP60474, a highly potent anti-endotoxemic agent, is a potentcyclin-dependent kinase (CDK)inhibitor (IC50 values are 26, 3, 4, 216, 10, 200 and 13nM for CDK1/B, CDK2/E, CDK2/A, CDK4/D, CDK5/p25, CDK7/H and...

YN330001 Peretinoin 81485-25-8

Peretinoin is an oral acyclic retinoid retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such asretinoid X receptor(RXR) and retinoic acid receptor (RAR).

YN321610 Pimethixene maleate 13187-06-9

Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimet...

YN320046 Treprostinil 81846-19-7

Treprostinil (LRX-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2nM, respectively.