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Ginsenoside Rg5 is the main component of Red ginseng. Ginsenoside blocks binding ofIGF-1to its receptor with an IC50 of ~90nM. Ginsenoside Rg5 also inhibits the mRNA expression ofCOX-2via suppression of the DNA binding ...
YN330596 Ginsenoside Rg5 186763-78-0
Ginsenoside Rg5 is the main component of Red ginseng. Ginsenoside blocks binding ofIGF-1to its receptor with an IC50 of ~90nM. Ginsenoside Rg5 also inhibits the mRNA expression ofCOX-2via suppression of the DNA binding ...
YN330625 [10]-Shogaol 36752-54-2
[10]-Shogaol is an antioxidant fromZingiber officinalefor human skin cell growth and a migration enhancer. [10]-Shogaol inhibits COX-2 with an IC50 of 7.5μM and has antiproliferation activity .
YN330626 [8]-Shogaol 36700-45-5
[8]-Shogaol, one of the pungent phenolic compounds in ginger, exhibits anti-platelet activity (IC50=5μM) and inhibits COX-2 (IC50=17.5μM). [8]-Shogaol induces apoptosis in human leukemia cells.
YN330531 Psoralidin 18642-23-4
Psoralidin, a naturally occurring coumestan isolated from the fractions of organic solvents such as ethylacetate, hexane, or n-butanol of the seed extract of Psoralea corylifolia L., has a variety of biological activities such as antican...
YN330542 (-)-Catechin gallate 130405-40-2
(-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity ofCOX-1 and COX-2enzymes.
Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds tocyclooxygenase (COX)-2active site.
YN330619 S-(+)-Marmesin 13849-08-6
Marmesin (S-(+)-Marmesin, (+)-Marmesin, (S)-Marmesin) is a natural coumarin with COX-2 and 5-LOX dual inhibitory activity.
YN251438 Macelignan 107534-93-0
Macelignan(Anwuligan) is a natural compound isolated from Myristica fragrans Houtt; possesses therapeutic potentials against neurodegenerative diseases with oxidative stress and neuroinflammation. in vitro: Macelignan significantly a...
YN330488 Bromfenac sodium 91714-93-1
Bromfenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.
YN330585 Anemarsaponin B 139051-27-7
Anemarsaponin B is a steroidal saponin isolated from the rhizomes ofA. asphodeloides(Liliaceae). Anemarsaponin B decreases the protein and mRNA levels ofiNOS and COX-2. Anemarsaponin B reduces the expressions and produc...
YN330623 N-trans-Feruloyltyramine 66648-43-9
N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid fromPiper nigru, is an inhibitor ofCOX1 and COX2, with potential antioxidant properties. N-trans-Feruloyltyramine possesses anti-inflammatory activity.
YN330554 Roburic acid 6812-81-3
Roburic acid, a tetracyclic triterpenoid found inGentiana macrophylla, acts as an inhibitor ofCOX, with IC50s of 5 and 9μM for COX-1 and COX-2, respectively.
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