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  • YN330596 Ginsenoside Rg5

    Ginsenoside Rg5 is the main component of Red ginseng. Ginsenoside blocks binding ofIGF-1to its receptor with an IC50 of ~90nM. Ginsenoside Rg5 also inhibits the mRNA expression ofCOX-2via suppression of the DNA binding ...

  • YN330596 Ginsenoside Rg5 186763-78-0

    Ginsenoside Rg5 is the main component of Red ginseng. Ginsenoside blocks binding ofIGF-1to its receptor with an IC50 of ~90nM. Ginsenoside Rg5 also inhibits the mRNA expression ofCOX-2via suppression of the DNA binding ...

  • YN330625 [10]-Shogaol 36752-54-2

    [10]-Shogaol is an antioxidant fromZingiber officinalefor human skin cell growth and a migration enhancer. [10]-Shogaol inhibits COX-2 with an IC50 of 7.5μM and has antiproliferation activity .

  • YN330626 [8]-Shogaol 36700-45-5

    [8]-Shogaol, one of the pungent phenolic compounds in ginger, exhibits anti-platelet activity (IC50=5μM) and inhibits COX-2 (IC50=17.5μM). [8]-Shogaol induces apoptosis in human leukemia cells.

  • YN330531 Psoralidin 18642-23-4

    Psoralidin, a naturally occurring coumestan isolated from the fractions of organic solvents such as ethylacetate, hexane, or n-butanol of the seed extract of Psoralea corylifolia L., has a variety of biological activities such as antican...

  • YN330542 (-)-Catechin gallate 130405-40-2

    (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity ofCOX-1 and COX-2enzymes.

  • YN330286 Paradol 27113-22-0

    Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds tocyclooxygenase (COX)-2active site.

  • YN330619 S-(+)-Marmesin 13849-08-6

    Marmesin (S-(+)-Marmesin, (+)-Marmesin, (S)-Marmesin) is a natural coumarin with COX-2 and 5-LOX dual inhibitory activity.

  • YN251438 Macelignan 107534-93-0

    Macelignan(Anwuligan) is a natural compound isolated from Myristica fragrans Houtt; possesses therapeutic potentials against neurodegenerative diseases with oxidative stress and neuroinflammation. in vitro: Macelignan significantly a...

  • YN330488 Bromfenac sodium 91714-93-1

    Bromfenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.

  • YN330585 Anemarsaponin B 139051-27-7

    Anemarsaponin B is a steroidal saponin isolated from the rhizomes ofA. asphodeloides(Liliaceae). Anemarsaponin B decreases the protein and mRNA levels ofiNOS and COX-2. Anemarsaponin B reduces the expressions and produc...

  • YN330642 Hamaudol 735-46-6

    Hamaudol is a chromone isolated fromSaposhnikovia divaricata. Hamaudol shows significant inhibitory activity oncyclooxygenase (COX)-1 and COX-2activities with IC50 values of 0.30, 0.57 mM, respectively, and has potent analgesi...

  • YN330623 N-trans-Feruloyltyramine 66648-43-9

    N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid fromPiper nigru, is an inhibitor ofCOX1 and COX2, with potential antioxidant properties. N-trans-Feruloyltyramine possesses anti-inflammatory activity.

  • YN330554 Roburic acid 6812-81-3

    Roburic acid, a tetracyclic triterpenoid found inGentiana macrophylla, acts as an inhibitor ofCOX, with IC50s of 5 and 9μM for COX-1 and COX-2, respectively.

  • YN330624 Sphondin 483-66-9

    Sphondin, isolated fromHeracleum laciniatum, possesses an inhibitory effect on IL-1β-induced increase in the level ofCOX-2protein and PGE2release in A549 cells.

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