YN350079 UM-164 903564-48-7

UM-164 is a highly potent, dual c-Src/p38inhibitor of c-Src with a binding constant Kd of 2.7 nM for c-Src and inhibits both p38α and p38β.

YN350065 AZ 628 878739-06-1

AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM in cell-free assays, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.

YN320358 (Z)-Thiothixene 3313-26-6

N/A

YN321657 Serotonin hydrochloride 153-98-0

Serotonin HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.

YN320455 Syk Inhibitor II 726695-51-8

Syk Inhibitor II is a potent, high selective and ATP-competitiveSykinhibitor with an IC50 of 41nM. Syk Inhibitor II inhibits5-HTrelease from RBL-cells with an IC50 of 460nM. Syk Inhibitor II shows less potent ag...

YN321265 Xanthotoxol 2009-24-7

Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.

YN330233 YQ128 2454246-18-3

YQ128 is a potent and selective second-generationNLRP3 (NOD-like receptor P3) inflammasomeinhibitor with an IC50 of 0.30 µM. YQ128 significantly and selectively suppresses the production ofIL-1β, but not TNF-α, a...

YN330535 Cardamonin 18956-16-6

Cardamonin, isolated from the fruits of Alpinia species, is a chalconoid with anti-inflammatory and anti-tumor activity. It has been shown to be a novel antagonist of hTRPA1 cation channel with IC50 of 454 nM while does not intera...

YN350220 Ginsenoside Re 52286-59-6

Ginsenoside Re is a major ginsenoside in ginseng and belongs to 20(S)-protopanaxatriol group. It has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions.

YN321589 Thioridazine hydrochloride 130-61-0

Thioridazine is a potent antianxiety and antipsychotic agent.

YN350053 Guggulsterone 95975-55-6

Guggulsterone is one of the active constituent of Commiphora mukul. It occurs in two isomeric forms, namely Z-GS and E-GS. Guggulsterone act as antagonist ligands for the bile acid receptor, farnesoid X receptor, and as active in...

YN350194 Anisomycin 22862-76-6

Anisomycin is an antibiotic, which inhibits protein synthesis, and also act as a JNK activator.

YN321066 UNBS5162 956590-23-1

UNBS5162 is a pan-antagonist ofCXCL chemokineexpression, with anti-tumor activity.

YN320432 L 888607 860033-06-3

L 888607 is a potent, and selectiveCRTH2(also known as DP2) agonist with a Ki of 0.8nM.

YN320112 Asenapine 65576-45-6

Asenapine is an antagonist ofserotonin receptors(5-HT2A, 5-HT2B, 5-HT2C, 5-HT6, 5-HT7),adrenoceptors(α1, α2A, α2B, α2C),dopamine receptors(D2, D3, D4) and histamine receptors(H1, H2), withpKis of 8.4-10.5, 8.9-9....