YN340016 TX1-85-1

TX1-85-1 is an irreversible Her3 (ErbB3)inhibitor with an IC50 of 23nM. TX1-85-1 is also the first selective Her3 lig and , which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces ...

YN340211 PD158780 171179-06-9

PD158780 is a potentEGFRfamily inhibitor with IC50s of 8 pM, 49, 52, 52nM for EGFR, ErbB2, ErbB3, and ErbB4, respectively.

YN340016 TX1-85-1 1603845-32-4

TX1-85-1 is an irreversible Her3 (ErbB3)inhibitor with an IC50 of 23nM. TX1-85-1 is also the first selective Her3 lig and , which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces ...