YN321716 Pectolinarin 28978-02-1

Pectolinarin, isolated fromCirsium chanroenicum, possesses anti-inflammatory activity. Pectolinarin inhibits secretion ofIL-6 and IL-8, as well as the production ofPGE2 and NO. Pectolinarin suppresses cell proliferation and i...

YN330436 Methylthiouracil 56-04-2

Methylthiouracil is an antithyroid preparation.

YN330612 β-Anhydroicaritin 38226-86-7

β-Anhydroicaritin is isolated fromBoswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties. β-Anhydroicaritin ameliorates the degrada...

YN330569 Mulberroside A 102841-42-9

Mulberroside A is one of the main bioactive constituent in mulberry (Morus albaL.). Mulberroside A decreases the expressions ofTNF-α,IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and ...

YN330056 LMT-28 1239600-18-0

LMT-28 is an orally active and the first syntheticIL-6inhibitor that functions through direct binding to gp130. LMT-28 shows low toxicity and selectively inhibits IL-6-induced phosphorylation of STAT3, JAK2, and gp130...

YN330453 Balsalazide 80573-04-2

Balsalazide (Colazal, Giazo), an aminosalicylate and oral prodrug, is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide suppress colitis-associated carcinogenesis through modulation...

YN330568 Ginsenoside Rh1 63223-86-9

Ginsenoside Rh1 is isolated from the root of Panax Ginseng. Ginsenoside Rh1 inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β.

YN330102 Resatorvid 243984-11-4

Resatorvid (TAK-242) is a selectiveToll-like receptor 4 (TLR4)inhibitor. Resatorvid inhibitsNO, TNF-R and IL-6production with IC50s of 1.8nM, 1.9nM and 1.3nM, respectively. Resatorvid downregulates expression of TL...

YN321653 Hydrocortisone hemisuccinate 2203-97-6

Hydrocortisone hemisuccinate (A-hydrocort, Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid with anti-inflammatory properties, is an inhibitor of proinflammatory cytokine with IC50 of 6.7 μM and 21.4 μM for <...