Resatorvid
Cat. No. :YN330102
CAS No. :243984-11-4
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order@ubiochem.com| Product Name: | Resatorvid |
| CAS NO.: | 243984-11-4 |
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| Molecular Weight: | 361.82 |
| Molecular Formula: | C₁₅H₁₇ClFNO₄S |
| SMILES: | O=S([C@H]1C(C(OCC)=O)=CCCC1)(NC2=CC=C(C=C2Cl)F)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Resatorvid (TAK-242) is a selectiveToll-like receptor 4 (TLR4)inhibitor. Resatorvid inhibitsNO, TNF-R and IL-6production with IC50s of 1.8nM, 1.9nM and 1.3nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibitsautophagy and plays pivotal role in various inflammatory diseases. |
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