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Resatorvid

Cat. No. :YN330102

  • CAS No. :243984-11-4

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    • Product Name:Resatorvid
      CAS NO.:243984-11-4
      Chemical Name:
      Synonyms:
      Molecular Weight:361.82
      Molecular Formula:C₁₅H₁₇ClFNO₄S
      SMILES:O=S([C@H]1C(C(OCC)=O)=CCCC1)(NC2=CC=C(C=C2Cl)F)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Resatorvid (TAK-242) is a selectiveToll-like receptor 4 (TLR4)inhibitor. Resatorvid inhibitsNO, TNF-R and IL-6production with IC50s of 1.8nM, 1.9nM and 1.3nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibitsautophagy and plays pivotal role in various inflammatory diseases.
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