YN340235 AT9283

AT9283 is a potent JAK2/3 inhibitor with IC50 of 1.2 nM/1.1 nM in cell-free assays also potent to Aurora A/B, Abl(T315I). Phase 2.

YN340235 AT9283 896466-04-9

AT9283 is a potent JAK2/3 inhibitor with IC50 of 1.2 nM/1.1 nM in cell-free assays also potent to Aurora A/B, Abl(T315I). Phase 2.

YN320351 Facinicline hydrochloride 677305-02-1

Facinicline hydrochloride (RG3487 hydrochloride) is an orally activenicotinic α7 receptorpartial agonist, with a Ki of 6nM for α7 human nAChR. Facinicline hydrochloride (RG3487 hydrochloride) improves cognition and sensorimot...

YN321382 Tropisetron 89565-68-4

Tropisetron is a 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.

YN320945 Sinomenine hydrochloride 6080-33-7

Sinomenine (SN), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.

YN360491 GTS-21 dihydrochloride 156223-05-1

GTS-21 dihydrochloride is a selective α7 nicotinic acetylcholine receptor agonist, has recently been established as a promising treatment for inflammation.

YN321281 INCB3344 1262238-11-8

INCB3344 is a potent, selective and orally bioavailableCCR2antagonist with IC50 values of 5.1nM (hCCR2) and 9.5nM (mCCR2) in binding antagonism and 3.8nM (hCCR2) and 7.8nM (mCCR2) in antagonism of chemotaxis...