Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN420263 Miransertib 1313881-70-7
Miransertib (ARQ-092) is a potent, selective and orally bioavailable allosteric inhibitor of Akt with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.
YN420221 KP-23172 1374996-60-7
KP372-1 is aPI3-K/Akt pathwayinhibitor extracted from patent US7196083.
YN420201 Ipatasertib dihydrochloride 1396257-94-5
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitivepan-Aktinhibitor with IC50s of 5, 18 and 8nM forAkt1,Akt2 and Akt3, respectively.
YN420002 BAY1125976 1402608-02-9
BAY 1125976 is a selective allosteric AKT1/2 inhibitor,exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models. BAY1125976 inhibits the activity of AKT1 (IC50 = 5.2 nM at 10 µM AT...
YN420117 Borussertib 1800070-77-2
Borussertib is a covalent-allosteric inhibitor of protein kinase Akt with an IC50 of 0.8 nM and a Ki of 2.2 nM for WT Akt.
YN420232 GSK2110183 analog 1 hydroch... 2070009-64-0
GSK2110183 analog 1 hydrochloride is the structural analogue of GSK2110183.
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