42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.
2-Aminobenzenesulfonamide is a molecule containing the sulfonamide functional group attached to an aniline
TBK1/IKKε-IN-1 is a dualTBK1 and IKKεinhibitor extracted from patent US20160376283 A1, Compound 274 in Example 60, hasIC50s of <100nM.
4-O-Methyl honokiol is a natural neolignan isolated fromMagnolia officinalis, acts as aPPARγagonist, and inhibtisNF-κBactivity, used for cancer and inflammation research.
LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities.
MCI826 is aP-glycoprotein(P-gp) antagonist.
Antitumor agent-4, a butenylphenyl phosphate derivative, is a drug for mammary cancer and anovulatory sterility.
L-771688 is a highly selectiveα1A-Adrenoceptorantagonist with a Ki of 0.43±0.02nM.