YN480802 42-(2-Tetrazolyl)rapamycin 221877-56-1 Cancer
42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.
YN372964 2-Aminobenzenesulfonamide 3306-62-5 Cancer
2-Aminobenzenesulfonamide is a molecule containing the sulfonamide functional group attached to an aniline
YN410154 TBK1/IKKε-IN-1 2058264-32-5 Cancer
TBK1/IKKε-IN-1 is a dualTBK1 and IKKεinhibitor extracted from patent US20160376283 A1, Compound 274 in Example 60, hasIC50s of <100nM.
YN410153 4-O-Methyl honokiol 68592-15-4 Cancer
4-O-Methyl honokiol is a natural neolignan isolated fromMagnolia officinalis, acts as aPPARγagonist, and inhibtisNF-κBactivity, used for cancer and inflammation research.
YN484272 LM985 87626-56-0 Cancer
LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities.
YN361075 MCI826 140646-80-6 Cancer
MCI826 is aP-glycoprotein(P-gp) antagonist.
YN484283 Antitumor agent-4 115767-64-1 Cancer
Antitumor agent-4, a butenylphenyl phosphate derivative, is a drug for mammary cancer and anovulatory sterility.
YN322049 L-771688 200050-59-5 Cancer
L-771688 is a highly selectiveα1A-Adrenoceptorantagonist with a Ki of 0.43±0.02nM.
YN310380 WD2000-012547 283172-68-9 Cancer
WD2000-012547 is a selective poly(ADP-ribose)-polymerase (PARP-1) inhibitor with a pKiof 8.221.
YN350269 p38 MAPK-IN-2 635725-16-5 Cancer
p38 MAPK-IN-2 is an inhibitor ofp38 kinase.
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