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> Products > Inhibitors & Agonists > Neuronal Signaling > Beta-secretase

(1α,1'S,4β)-Lanabecestat

Cat. No. :YN380012

  • CAS No. :1384082-96-5

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    • Product Name:(1α,1'S,4β)-Lanabecestat
      CAS NO.:1384082-96-5
      Chemical Name:
      Synonyms:
      Molecular Weight:412.53
      Molecular Formula:C₂₆H₂₈N₄O
      SMILES:NC(C(C)=N1)=N[C@]21C3=C(C=CC(C4=CC(C#CC)=CN=C4)=C3)C[C@]52CC[C@@H](OC)CC5
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is aBeta site APP Cleaving Enzymel (BACE1)inhibitor extracted from patent WO2012087237A1, compound 20a, hasIC50s of 2.2nM (TR-FRET assay) and 0.28nM (sAPPprelease assay), respectively.
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