SSR240612
Cat. No. :YN320942
CAS No. :464930-42-5
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5mg
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Product Name: | SSR240612 |
CAS NO.: | 464930-42-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 793.41 |
Molecular Formula: | C₄₂H₅₃ClN₄O₇S |
SMILES: | O=S(N[C@@H](C1=CC=C2C(OCO2)=C1)CC(N[C@@H](C(N(C)C(C)C)=O)CC3=CC=C(CN([C@@H]4C)[C@H](CCC4)C)C=C3)=O)(C5=CC(C=CC(OC)=C6)=C6C=C5)=O.Cl[H] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | SSR240612 is a potent, and orally active specific non-peptidebradykinin B1 receptorantagonist, with Kis of 0.48nM and 0.73nM for B1 kinin receptors of human fibroblast MRC5 and HEK cells expressing human B1 receptors, 481nM and 358nM for B2 receptors of guinea pig ileum membranes and CHO cells expressing human B1 receptor, respectively. |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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