GLPG1837
Cat. No. :YN360258
CAS No. :1654725-02-6
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order@ubiochem.com| Product Name: | GLPG1837 |
| CAS NO.: | 1654725-02-6 |
| Chemical Name: | |
| Synonyms: | ABBV-974 |
| Molecular Weight: | 348.42 |
| Molecular Formula: | C₁₆H₂₀N₄O₃S |
| SMILES: | O=C(C1=NNC=C1)NC(S2)=C(C(N)=O)C3=C2C(C)(C)OC(C)(C)C3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | GLPG1837 is a novel CFTR potentiator with an EC50 value of 3 nM for F508del, showing enhanced efficacy on CFTR mutants harboring class III mutations compared to Ivacaftor. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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