PG01
Cat. No. :YN360134
CAS No. :853138-65-5
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order@ubiochem.com| Product Name: | PG01 |
| CAS NO.: | 853138-65-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 439.55 |
| Molecular Formula: | C₂₈H₂₉N₃O₂ |
| SMILES: | O=C(N(C)C(C1=CC=CC=C1)C(NC2=CC=C(C(C)C)C=C2)=O)CC3=CNC4=C3C=CC=C4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PG01 is a potentCFTRCl-channel potentiator. PG01 can correct gating defects ofCFTRmutants, is effective on b>E193K,G970R and G551D(CFTR mutants) withKdvalues of 0.22μM, 0.45μM and 1.94μM, respectively. PG01 is also effective onΔF508(Kaof 0.3μM). PG01 increasesΔF508-CFTRCl-current after adding Forskolin. |
| IC50&Target: | |
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| References: |
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