SC-236
Cat. No. :YN330703
CAS No. :170569-86-5
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Product Name: | SC-236 |
CAS NO.: | 170569-86-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 401.79 |
Molecular Formula: | C₁₆H₁₁ClF₃N₃O₂S |
SMILES: | O=S(C1=CC=C(N2N=C(C(F)(F)F)C=C2C3=CC=C(Cl)C=C3)C=C1)(N)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | SC-236 is an orally activeCOX-2specific inhibitor (IC50= 10nM) and aPPARγagonist. SC-236 supresses activator protein-1 (AP-1) through c-Jun NH2-terminal kinase. SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model . |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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