Chemical structure
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CAS no.
Target
BAY885 is a highly potent and selectiveERK5inhibitor with an IC50 of 35nM. BAY885 shows weak inhibition on others kinases.
Hypothemycin, a fungal polyketide, is a multikinase inhibitor with Kis of 10/70nM, 17/38nM, 90nM, 900nM/1.5μM, and 8.4/2.4μM forVEGFR2/VEGFR1,MEK1/MEK2,FLT-3,PDGFRβ/PDGFRα, and ERK1/ERK2, re...
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