Alvelestat
Cat. No. :YN372322
CAS No. :848141-11-7
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Product Name: | Alvelestat |
CAS NO.: | 848141-11-7 |
Chemical Name: | |
Synonyms: | Avelestat |
Molecular Weight: | 545.53 |
Molecular Formula: | C₂₅H₂₂F₃N₅O₄S |
SMILES: | O=C(C1=CC(C2=CC=NN2C)=C(C)N(C3=CC=CC(C(F)(F)F)=C3)C1=O)NCC4=NC=C(S(=O)(C)=O)C=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases. Phase 2. |
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References: |
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