Freselestat
Cat. No. :YN372323
CAS No. :208848-19-5
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order@ubiochem.com| Product Name: | Freselestat |
| CAS NO.: | 208848-19-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 452.51 |
| Molecular Formula: | C₂₃H₂₈N₆O₄ |
| SMILES: | O=C(NC(C(C1=NN=C(C(C)(C)C)O1)=O)C(C)C)CN(C(C2=CC=CC=C2)=NC=C3N)C3=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Freselestat (ONO-6818) is a potent and orally activeneutrophil elastaseinhibitor with a Ki of 12.2nM. Freselestat is >100-fold less-active against other proteases such as trypsin, protein-ase 3, pancreatic elastase, plasmin, thrombin, collagenase, cathepsin G, and murine macrophage elastase. Freselestat has a potent anti-inflammatory activity. |
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