PF-562271
Cat. No. :YN440096
CAS No. :717907-75-0
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Product Name: | PF-562271 |
CAS NO.: | 717907-75-0 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 507.49 |
Molecular Formula: | C₂₁H₂₀F₃N₇O₃S |
SMILES: | CS(=O)(N(C)C1=NC=CC=C1CNC2=NC(NC3=CC4=C(C=C3)NC(C4)=O)=NC=C2C(F)(F)F)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. |
IC50&Target: | |
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References: |
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