CHIR-99021
Cat. No. :YN420029
CAS No. :252917-06-9
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order@ubiochem.com| Product Name: | CHIR-99021 |
| CAS NO.: | 252917-06-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 465.34 |
| Molecular Formula: | C₂₂H₁₈Cl₂N₈ |
| SMILES: | N#CC1=CC=C(N=C1)NCCNC2=NC=C(C(C3=CC=C(Cl)C=C3Cl)=N2)C4=NC=C(N4)C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CHIR-99021 (CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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