R547
Cat. No. :YN420004
CAS No. :741713-40-6
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order@ubiochem.com| Product Name: | R547 |
| CAS NO.: | 741713-40-6 |
| Chemical Name: | |
| Synonyms: | Ro 4584820 |
| Molecular Weight: | 441.45 |
| Molecular Formula: | C₁₈H₂₁F₂N₅O₄S |
| SMILES: | O=S(N1CCC(NC2=NC(N)=C(C(C3=C(C(F)=CC=C3OC)F)=O)C=N2)CC1)(C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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