LY2090314
Cat. No. :YN420236
CAS No. :603288-22-8
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Product Name: | LY2090314 |
CAS NO.: | 603288-22-8 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 512.53 |
Molecular Formula: | C₂₈H₂₅FN₆O₃ |
SMILES: | O=C(C(C1=CN2CCN(C(N3CCCCC3)=O)CC4=CC(F)=CC1=C42)=C5C6=CN=C7C=CC=CN76)NC5=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 is highly selective towards GSK3 as demonstrated by its fold selectivity relative to a large panel of kinases. |
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