KY19382
Cat. No. :YN420153
CAS No. :2226664-93-1
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5mg
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order@ubiochem.com| Product Name: | KY19382 |
| CAS NO.: | 2226664-93-1 |
| Chemical Name: | |
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| Molecular Weight: | 360.19 |
| Molecular Formula: | C₁₇H₁₁Cl₂N₃O₂ |
| SMILES: | O=C1NC2=C(C=C(Cl)C(Cl)=C2)/C1=C3NC4=C(C=CC=C4)C/3=N/OC |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | KY19382 is a potent and orally active dual inhibitor ofCXXC5-DVL and GSK3β, with IC50s of 19 and 10nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases. |
| IC50&Target: | |
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