Picropodophyllin
Cat. No. :YN440328
CAS No. :477-47-4
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Product Name: | Picropodophyllin |
CAS NO.: | 477-47-4 |
Chemical Name: | |
Synonyms: | AXL1717 |
Molecular Weight: | 414.41 |
Molecular Formula: | C₂₂H₂₂O₈ |
SMILES: | O=C1OC[C@]2([H])[C@@H](O)C3=C(C=C4OCOC4=C3)[C@@H](C5=CC(OC)=C(OC)C(OC)=C5)[C@@]21[H] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Picropodophyllin (PPP) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R). |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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