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Picropodophyllin

Cat. No. :YN440328

  • CAS No. :477-47-4

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    • Products Infomation
    • Biological Activity
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    • Product Name:Picropodophyllin
      CAS NO.:477-47-4
      Chemical Name:
      Synonyms:AXL1717
      Molecular Weight:414.41
      Molecular Formula:C₂₂H₂₂O₈
      SMILES:O=C1OC[C@]2([H])[C@@H](O)C3=C(C=C4OCOC4=C3)[C@@H](C5=CC(OC)=C(OC)C(OC)=C5)[C@@]21[H]
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Picropodophyllin (PPP) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR(FGF-R, PDGF-R, OR EGF-R).
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