I-OMe-Tyrphostin AG 538
Cat. No. :YN440280
CAS No. :1094048-77-7
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order@ubiochem.com| Product Name: | I-OMe-Tyrphostin AG 538 |
| CAS NO.: | 1094048-77-7 |
| Chemical Name: | |
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| Molecular Weight: | 437.19 |
| Molecular Formula: | C₁₇H₁₂INO₅ |
| SMILES: | N#C/C(C(C1=CC=C(O)C(O)=C1)=O)=CC2=CC(OC)=C(O)C(I)=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor ofIGF-1R(insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor ofphosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC50 of 1 µM. |
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