YN482137 Sodium gualenate 6223-35-4

Sodium gualenate (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound, which is gradually decomposed in the solid state at room temperature. It has anti-inflammatory and wound-healing eff...

YN300060 Meclofenamate sodium 6385-02-0

Meclofenamate Sodium is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea.

YN251290 Amodiaquine dihydrochloride d... 6398-98-7

Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.

YN480702 Traumatic Acid 6402-36-4

Traumatic Acid is a monounsaturated dicarboxylic acid isolated fromPhaseolus vulgaris. Traumatic Acid can cause a decrease in membrane phospholipid peroxidation and show antioxidant and stimulatory effects oncollagen biosynthesis....

YN280149 Sedanolide 6415-59-4

Sedanolide, a natural compound occurring in edible umbelliferous plants, possesses anti-inflammatory and antioxidant activities.

YN482929 Taraxasteryl acetate 6426-43-3

Taraxasteryl acetate is isolated fromP. sagittalis, and has a broad spectrum ofanti-inflammatoryactivity. Taraxasteryl acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema. Taraxasteryl acetate can be us...

YN420288 Sophocarpine 6483-15-4

Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.

YN330313 VGX-1027 6501-72-0

VGX-1027 is an orally active immunomodulator. Phase 1.

YN373352 D-Glucuronic acid 6556-12-3

D-Glucuronic acid is a key intermediate metabolite of the uronic acid pathway and may plays a role in the detoxification of certain drugs.

YN440429 6-Demethoxytangeretin 6601-66-7

6-Demethoxytangeretin is a citrus flavonoid isolated fromCitrus depressa. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast ce...

YN483547 6-Hydroxyflavone 6665-83-4

6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK s...

YN483546 7-Hydroxyflavone 6665-86-7

7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0.015 μM and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2. It also has excellent antioxidant properties and great potential to be applied as ...

YN321730 Jatrorrhizine chloride 6681-15-8

Jatrorrhizine hydrochloride can inhibit the proliferation and neovascularization of C8161 metastatic melanoma cells with low toxicity, suggests that jatrorrhizine hydrochloride is a potential new antimelanoma drug candidate. Jatrorrhizin...

YN482684 Kaurenoic acid 6730-83-2

Kaurenoic acid has cytotoxic and embryotoxic effects. Kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level, an indicator of lipoperoxidation in colon tissue. Kaurenoic acid exerts a u...

YN251922 3-Deazaadenosine 6736-58-9

3-Deazaadenosine is an inhibitor ofS-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM; 3-Deazaadenosine has anti-inflammatory, anti-proliferative and anti-HIVactivity.

YN482769 Isorhamnetin 3-O-galactoside 6743-92-6

Isorhamnetin 3-O-galactoside (Cacticin), a flavonoid glycoside isolated fromArtemisia capillarisThunberg, which ameliorates CCl4-induced hepatic damage by enhancing the anti-oxidative defense system and reducing the inflammatory si...

YN330647 α-Humulene 6753-98-6

α-Humulene is a main constituent ofTanacetum vulgareL. (Asteraceae) essential oil with anti-inflammation (IC50=15±2 µg/mL). α-Humulene inhibitsCOX-2 and iNOSexpression.

YN410025 Helenalin 6754-13-8

Helenalin is an anti-inflammatory sesquiterpene lactone. Helenalin selectively inhibits transcription factorNF-κBby directly targeting p65. Helenalin has alkylating activity, targets the cysteine sulfhydryl groups in the p65 subunit ...

YN482718 Mesaconine 6792-09-2

Mesaconinean, an ingredient fromAconitum carmichaeliiDebx., has cardiac effect.

YN270432 Escin 6805-41-0

Escin is a mixture of saponins with anti-inflammatory, vasoconstrictor and vasoprotective effects found in Aesculus hippocastanum(the horse chestnut).