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Metabolic Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN321541 Triamterene 396-01-0

    Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner with IC50 of 4.5 μM.

  • YN481810 DL-Carnitine 406-76-8

    DL-Carnitine is a racemic mixture of L-Carnitine and D-Carnitine, regulates fatty acid transport in mitochondria, elevates serum carnitine fractions.

  • YN482064 Perflubron 423-55-2

    Perflubron (1-Bromoperfluorooctane, Perfluorooctyl bromide, Oxygent, PFOB) exhibits anti-inflammatory activity thus decreases cytokine production in human alveolar macrophages. Perflubron also attenuates oxidative damage<...

  • YN372752 Lithocholic acid 434-13-9

    Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR.

  • YN483281 Gentianine 439-89-4

    Gentianine, an active metabolite of Swertiamarin, has anti-diabetic effect and anti-inflammatory property.

  • YN370707 Homogentisic acid 451-13-8

    Homogentisic acid is a specific metabolite in urine and serum, which is used for diagnosis of alkaptonuria.

  • YN484172 Glyhexamide 451-71-8

    Glyhexamide is an effective hypoglycemic agent in adult diabetics.

  • YN330484 (±)-Carnitine chloride 461-05-2

    DL-Carnitine HCl is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.

  • YN374096 4,4'-Disulfanediylbis(2-amino... 462-10-2

    4,4'-Disulfanediylbis(2-aminobutanoic acid) is an endogenous metabolite.

  • YN483485 Marrubiin 465-92-9

    Marrubiin, isolated fromMarrubium vulgare, exhibits vasorelaxant and antioedematogenic activity. Marrubiin alleviates diabetic symptoms in animals .

  • YN481190 (-)-Cedrene 469-61-4

    (-)-Cedrene (α-cedrene) is a sesquiterpene constituent of cedarwood oils, with anti-leukemic, antimicrobial and anti-obesity activities.

  • YN360995 Marinobufogenin 470-42-8

    Marinobufogenin is a strong inhibitor ofNa+/K+ATPasethat has been identified in mammalian plasma.

  • YN482765 Steviol 471-80-7

    Steviol (Hydroxydehydrostevic acid, Hydroxy Dehydrostevic Acid, NSC 226902), a major metabolite of the sweetening compound stevioside, inhibits CFTR activity, reduces AQP2 expression and promotes AQP2 degradation.

  • YN360993 Beta-Eudesmol 473-15-4

    Beta-Eudesmol is a natural oxygenated sesquiterpene, activateshTRPA1, with an EC50 of 32.5μM. Beta-Eudesmol increases appetite through TRPA1.

  • YN374306 DL-Glyceric Acid 473-81-4

    DL-Glyceric Acid is a compound that is secreted excessively in the urine by patients suffering from D-glyceric aciduria.

  • YN372682 Chenodeoxycholic Acid 474-25-9

    Chenodeoxycholic Acid is a naturally occurring human bile acid, and inhibits production of cholesterol in the liver and absorption in the intestines.

  • YN373070 Lumisterol 474-69-1

    Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol. Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities.

  • YN360597 24(S)-Hydroxycholesterol 474-73-7

    24(S)-Hydroxycholesterol (24S-OHC), the major brain cholesterol metabolite, plays an important role to maintain homeostasis of cholesterol in the brain. 24(S)-Hydroxycholesterol (24S-OHC) is one of the most efficient endogenousL...

  • YN483055 Cotoin 479-21-0

    Cotoin is a natural product isolated from the stem bark ofGarcinia virgate.

  • YN251899 Phloracetophenone 480-66-0

    Phloracetophenone (2,4,6-trihydroxyacetophenone) is the aglycone part of acetophenone glycoside obtained fromCurcuma comosaRoxb, with cholesterol-lowering activity. Phloracetophenone enhances cholesterol 7α-hydroxylase (CYP7A1) act...

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