YN450146 L-Quebrachitol 642-38-6

L-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation ofBMP-2, runt-related transcription factor-2 (Runx2),MAPK(ERK, JNK, p38α), and Wnt/β-cateninsignaling pathway.

YN373312 D-chiro-Inositol 643-12-9

D-chiro-Inositol is an epimer ofmyo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatmen...

YN374287 4-Methylbiphenyl 644-08-6

4-Methylbiphenyl is an endogenous metabolite.

YN410024 2-Hydroxychalcone 644-78-0

2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB .

YN370754 Imidazoleacetic acid 645-65-8

Imidazoleacetic acid is an endogenous lig and that stimulatesimidazole receptors.

YN374264 2'-Deoxyadenosine-5'-monophos... 653-63-4

2'-Deoxyadenosine-5'-monophosphate is an endogenous metabolite.

YN374039 2,6-Dimethylhydroquinone 654-42-2

2,6-Dimethylhydroquinone is an endogenous metabolite.

YN420283 Metformin 657-24-9

Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin indu...

YN374259 5-Aminovaleric acid 660-88-8

5-Aminovaleric acid is believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weakGABAagonist.

YN373333 Agaric acid 666-99-9

Agaric acid (Agaricinic Acid) is obtained from various plants of the fungous tribe, i.e.Polyporus officinalis and Polyporus igniarius. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine ...

YN370392 DL-Mevalonolactone 674-26-0

DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD...

YN374356 2-Piperidone 675-20-7

2-Piperidone is an endogenous metabolite.

YN484308 2-Bromoacetamide 683-57-8

2-Bromoacetamide can inactivate alcohol dehydrogenase.

YN420286 Buformin 692-13-7

Buformin (1-Butylbiguanide) is a potent and orally active biguanideantidiabetic agent, anAMPKactivator. Buformin decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin also has anti-cancer activi...

YN373371 5,6-Dihydro-5-methyluracil 696-04-8

5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels.

YN374029 4-Hydroxybenzylamine 696-60-6

4-Hydroxybenzylamine is an endogenous metabolite.

YN374060 2-Hydroxy-4-methylbenzaldehyd... 698-27-1

2-Hydroxy-4-methylbenzaldehyde is an endogenous metabolite.

YN374381 2,6-Dihydroxyacetophenone 699-83-2

2,6-Dihydroxyacetophenone is an endogenous metabolite.

YN310137 Nudifloramide 701-44-0

Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibitspoly(ADP-ribose) polymerase (PARP-1)activity in vitro.

YN374283 H-Gly-Pro-OH 704-15-4

H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.