YN360180 Azosemide 27589-33-9

Azosemide, a sulfonamide loop diuretic, is a potentNKCC1inhibitor with IC50s of 0.246 µM and 0.197 µM for hNKCC1A and NKCC1B, respectively.

YN372376 (-)-Hydroxycitric acid 27750-10-3

(-)-Hydroxycitric acid (Garcinia acid) is the principal acid of fruit rinds ofGarcinia cambogia. (-)-Hydroxycitric acid is a potent and competitive inhibitor ofATP citrate lyase. (-)-Hydroxycitric acid suppresses the fatty acid sy...

YN373404 (-)-Hydroxycitric acid lacton... 27750-13-6

(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor ofATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyze...

YN322100 Uridine-5'-diphosphate disodi... 27821-45-0

Uridine-5'-diphosphate disodium salt is a potent, selectiveP2Y6receptor native agonist (EC50=300nM;pEC50=6.52) and a potentP2Y14antagonist (pEC50=7.28). Uridine-5'-diphosphate disodium salt, anendogenous metabolite, catalyzes...

YN480478 Deacetylanisomycin 27958-06-1

Deacetylanisomycin is a potent growth regulator in plants and an inactive derivative of Anisomycin. Anisomycin is a potent protein synthesis inhibitor.

YN482776 Cimigenoside 27994-11-2

Cimigenoside is an active compound from genusCimicifuga.

YN371146 5-Methoxy-DL-tryptophan 28052-84-8

5-Methoxy-DL-tryptophan is an endogenous metabolite.

YN370676 Hydroxyphenylacetylglycine 28116-23-6

Hydroxyphenylacetylglycine is an acyl glycine, and an endogenous human metabolite.

YN360189 α-Cyano-4-hydroxycinnamic ac... 28166-41-8

4-Chloro-α-cyanocinnamic acid (α-CHCA) is a classic monocarboxylate transporters (MCT) inhibitor. α-cyano-4-hydroxycinnamate (CHC) has a 10-fold selectivity for MCT1 compared to other MCTs.

YN483434 Neochebulagic acid 28196-46-5

Neochebulagic acid is isolated fromPhyllanthus emblicaL..

YN1720031 Glucagon hydrochloride 28270-04-4

Glucagon hydrochloride (Porcine glucagon hydrochloride) is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis. Glucagon hydrochloride activates HNF4α and increases HNF4α phosp...

YN370741 L-Glyceric acid 28305-26-2

L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distingui...

YN482986 7-O-Geranylscopoletin 28587-43-1

7-O-Geranylscopoletin is a coumarin from the root ofAtalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia...

YN420303 Euphorbiasteroid 28649-59-4

Euphorbiasteroid, a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway and induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a ...

YN374105 4-(1,2-Dihydroxyethyl)benzene... 28822-73-3

4-(1,2-Dihydroxyethyl)benzene-1,2-diol, a normal norepinephrine metabolite, is found to be associated with Menkes syndrome.

YN374205 Adrenic Acid 28874-58-0

Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a naturally polyunsaturated fatty acid in the adrenal gl and , brain, kidney, and vasculature. Adrenic Acid can regulate the vascular tone in arteries of the adrenal cortex. Adr...

YN374072 L-Allothreonine 28954-12-3

L-Allothreonine (H-allo-Thr-OH) is an endogenous metabolite.