PIN1 inhibitor API-1
Cat. No. :YN310142
CAS No. :680622-70-2
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order@ubiochem.com| Product Name: | PIN1 inhibitor API-1 |
| CAS NO.: | 680622-70-2 |
| Chemical Name: | |
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| Molecular Weight: | 366.30 |
| Molecular Formula: | C₁₅H₁₃F₃N₆O₂ |
| SMILES: | O=C(NCC1=CC=C(COC2=C3NC=NC3=NC(N)=N2)C=C1)C(F)(F)F |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor with IC50 of 72.3 nM. PIN1 inhibitor API-1 targets Pin1 peptidyl-prolyl isomerase domain and inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 up-regulates miRNA biogenesis by retaining active XPO5 conformation and suppresses HCC development. |
| IC50&Target: | |
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