LIN28 inhibitor LI71
Cat. No. :YN310168
CAS No. :1357248-83-9
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order@ubiochem.com| Product Name: | LIN28 inhibitor LI71 |
| CAS NO.: | 1357248-83-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 335.40 |
| Molecular Formula: | C₂₁H₂₁NO₃ |
| SMILES: | O=C(O)C1=CC=C([C@@H]2NC3=C(C=CC=C3OCC)[C@@]4([H])[C@]2([H])CC=C4)C=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | LIN28 inhibitor LI71 is a potent and cell-permeableLIN28inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells. |
| IC50&Target: | |
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