Pimethixene maleate
Cat. No. :YN321610
CAS No. :13187-06-9
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order@ubiochem.com| Product Name: | Pimethixene maleate |
| CAS NO.: | 13187-06-9 |
| Chemical Name: | |
| Synonyms: | Pimetixene maleate |
| Molecular Weight: | 409.50 |
| Molecular Formula: | C₂₃H₂₃NO₄S |
| SMILES: | CN1CC/C(CC1)=C2C3=C(SC4=C2C=CC=C4)C=CC=C3.OC(/C=CC(O)=O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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