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NMS-P118

Cat. No. :YN310309

  • CAS No. :1262417-51-5

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    • Products Infomation
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    • Product Name:NMS-P118
      CAS NO.:1262417-51-5
      Chemical Name:
      Synonyms:
      Molecular Weight:395.42
      Molecular Formula:C₂₀H₂₄F₃N₃O₂
      SMILES:FC(CC1)(F)CCC1N(CC2)CCC2N(C3=O)CC4=C3C(C(N)=O)=CC(F)=C4
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively).
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