NMS-P118
Cat. No. :YN310309
CAS No. :1262417-51-5
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5mg
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Product Name: | NMS-P118 |
CAS NO.: | 1262417-51-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 395.42 |
Molecular Formula: | C₂₀H₂₄F₃N₃O₂ |
SMILES: | FC(CC1)(F)CCC1N(CC2)CCC2N(C3=O)CC4=C3C(C(N)=O)=CC(F)=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively). |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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