EB-47 dihydrochloride
Cat. No. :YN310096
CAS No. :1190332-25-2
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5mg
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Product Name: | EB-47 dihydrochloride |
CAS NO.: | 1190332-25-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 610.45 |
Molecular Formula: | C₂₄H₂₉Cl₂N₉O₆ |
SMILES: | O=C1NCC2=C(C=CC=C21)NC(CN3CCN(CC3)C([C@H]4O[C@H]([C@@H]([C@@H]4O)O)N5C6=C(N=C5)C(N)=NC=N6)=O)=O.[H]Cl.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | EB-47 dihydrochloride, a potent and selectivePARP-1/ARTD-1inhibitor with an IC50 value of 45nM, shows modest potency against ARTD5 with an IC50 value of 410nM. EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite. |
IC50&Target: | |
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References: |
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