Dehydrocorydaline
Cat. No. :YN310345
CAS No. :30045-16-0
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order@ubiochem.com| Product Name: | Dehydrocorydaline |
| CAS NO.: | 30045-16-0 |
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| Molecular Weight: | 366.43 |
| Molecular Formula: | C₂₂H₂₄NO₄+ |
| SMILES: | CC1=C(C=CC(OC)=C2OC)C2=C[N+]3=C1C4=CC(OC)=C(OC)C=C4CC3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Dehydrocorydaline exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSCLC cells. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). Dehydrocorydaline has anti-inflammatory and antinociceptive effects. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP. |
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