Niraparib hydrochloride
Cat. No. :YN310077
CAS No. :1038915-64-8
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Product Name: | Niraparib hydrochloride |
CAS NO.: | 1038915-64-8 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 356.85 |
Molecular Formula: | C₁₉H₂₁ClN₄O |
SMILES: | NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailablePARP1 and PARP2inhibitor with IC50s of 3.8 and 2.1nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activatesapoptosis and shows anti-tumor activity . |
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