5,7,4'-Trimethoxyflavone
Cat. No. :YN310372
CAS No. :5631-70-9
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Product Name: | 5,7,4'-Trimethoxyflavone |
CAS NO.: | 5631-70-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 312.32 |
Molecular Formula: | C₁₈H₁₆O₅ |
SMILES: | COC1=C(C(C=C(C2=CC=C(OC)C=C2)O3)=O)C3=CC(OC)=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | 5,7,4'-Trimethoxyflavone is isolated fromKaempferia parviflora(KP) that is a famous medicinal plant from Thail and . 5,7,4'-Trimethoxyflavone inducesapoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation ofcaspase-3, and degradation ofpoly (ADP-ribose) polymerase (PARP)protein.5,7,4'-Trimethoxyflavone is significantly effective at inhibiting proliferation of SNU-16 human gastric cancer cells in a concentration dependent manner. |
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