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Ac-FLTD-CMK

Cat. No. :YN330106

  • CAS No. :2376255-48-8

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    • Products Infomation
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    • Product Name:Ac-FLTD-CMK
      CAS NO.:2376255-48-8
      Chemical Name:
      Synonyms:
      Molecular Weight:569.05
      Molecular Formula:C₂₆H₃₇ClN₄O₈
      SMILES:ClCC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@@H](NC(C)=O)CC1=CC=CC=C1)=O)=O)=O)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specificinflammatory caspasesinhibitor. Ac-FLTD-CMK is effective againstcaspases-1(IC50 of 46.7nM),caspases-4(IC50 of 1.49μM),caspases-5(IC50 of 329nM), and caspases-11, but not the apoptotic caspases such as caspase-3.
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