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Polyphyllin VI

Cat. No. :YN330586

  • CAS No. :55916-51-3

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    • Products Infomation
    • Biological Activity
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    • Product Name:Polyphyllin VI
      CAS NO.:55916-51-3
      Chemical Name:
      Synonyms:
      Molecular Weight:738.90
      Molecular Formula:C₃₉H₆₂O₁₃
      SMILES:O[C@]1([C@@]2([H])O[C@]3(CC[C@@H](C)CO3)[C@H]1C)[C@]([C@@]4([H])C2)(CC[C@@]5([H])[C@@]4([H])CC=C6[C@@]5(CC[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]7O)([H])[C@@H]7O[C@@](O[C@@H](C)[C@H](O)[C@H]8O)([H])[C@@H]8O)C6)C)C
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Polyphyllin VI and polyphyllin VII possess anti-cancer activities, they exhibits strong inhibitory effects on lung cancer cell growth in vitro and in vivo by inducing G2/M cell cycle arrest and triggering apoptosis. Polyphyllin VI can inhibit 1,2-dimethylhydrazine(DMH)/dextran sodium sulfate(DSS)- induced colon tumor formation in institute of Cancer Research(ICR) mice partly through inducing apoptosis of abnormal colonic epithelial cells via the intrinsic pathway of apoptosis.
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