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SNIPER(ABL)-033

Cat. No. :YN430060

  • CAS No. :2222354-18-7

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    • Products Infomation
    • Biological Activity
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    • Product Name:SNIPER(ABL)-033
      CAS NO.:2222354-18-7
      Chemical Name:
      Synonyms:
      Molecular Weight:1211.42
      Molecular Formula:C₆₁H₇₃F₃N₁₀O₉S₂
      SMILES:CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCOC6=CC(C(C7=CSC([C@H]8N(C([C@H](C9CCCCC9)NC([C@H](C)NC)=O)=O)CCC8)=N7)=O)=CC=C6)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP lig and ) with a linker, induces the reduction of BCR-ABL protein with a DC50of 0.3μM.
      IC50&Target:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
      References:
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