CDDO-Im
Cat. No. :YN410069
CAS No. :443104-02-7
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Product Name: | CDDO-Im |
CAS NO.: | 443104-02-7 |
Chemical Name: | |
Synonyms: | CDDO-Imidazolide, RTA-403, TP-235 |
Molecular Weight: | 541.72 |
Molecular Formula: | C₃₄H₄₃N₃O₃ |
SMILES: | CC(C)([C@]1([H])CC[C@@]([C@@]2(CC[C@]3(CCC(C)(C[C@@]3([H])[C@]24[H])C)C(N5C=CN=C5)=O)C)6C)C(C(C#N)=C[C@]1(C)C6=CC4=O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | CDDO-Im (CDDO-Imidazolide, RTA-403, TP-235) is an activator of nuclear factor erythroid 2–related factor 2 (Nrf2) and peroxisome proliferator-activated receptor (PPAR). CDDO-Im binds to PPARα and PPARγ with Ki of 232 nM and 344 nM, respectively. CDDO-Im inhibits inflammatory response and tumor growth in vivo. |
IC50&Target: | |
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References: |
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