CDDO-dhTFEA
Cat. No. :YN410019
CAS No. :1191265-33-4
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order@ubiochem.com| Product Name: | CDDO-dhTFEA |
| CAS NO.: | 1191265-33-4 |
| Chemical Name: | |
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| Molecular Weight: | 574.72 |
| Molecular Formula: | C₃₃H₄₅F₃N₂O₃ |
| SMILES: | CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CCC(C)(C[C@]2([C@]13[H])[H])C)C(NCC(F)(F)F)=O)C)4C)5[H])C(C(C#N)=C[C@]5(C)[C@@]4([H])CC3=O)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activatesNrf2 and inhibits the pro-inflammatory transcription factorNF-κB. CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats. |
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