VE-821
Cat. No. :YN420194
CAS No. :1232410-49-9
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Product Name: | VE-821 |
CAS NO.: | 1232410-49-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 368.41 |
Molecular Formula: | C₁₈H₁₆N₄O₃S |
SMILES: | O=C(NC1=CC=CC=C1)C2=NC(C3=CC=C(C=C3)S(=O)(C)=O)=CN=C2N |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM in cell-free assays, shows inhibition of H2AX phosphorylation, minimal activity against PIKKs ATM, DNA-PK, mTOR and PI3Kγ. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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