(S)-Ceralasertib
Cat. No. :YN420260
CAS No. :1352226-87-9
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order@ubiochem.com| Product Name: | (S)-Ceralasertib |
| CAS NO.: | 1352226-87-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 412.51 |
| Molecular Formula: | C₂₀H₂₄N₆O₂S |
| SMILES: | O=[S@](C1(CC1)C2=NC(C3=C4C(NC=C4)=NC=C3)=NC(N5CCOC[C@H]5C)=C2)(C)=N |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | (S)-Ceralasertib ((S)-AZD6738) is extracted from patent WO2011154737A1, Compound II, exhibits an IC50 of 2.578nM. (S)-Ceralasertib is a potent and selective sulfoximine morpholinopyrimidineATRinhibitor with excellent preclinical physicochemical and pharmacokinetic (PK) characteristics. (S)-Ceralasertib is developed improving aqueous solubility and eliminates CYP3A4 time-dependent inhibition. |
| IC50&Target: | |
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