YN251837 Siomycin A 12656-09-6

Siomycin A is a thiopeptide antibiotic and is aForkhead box M1(FOXM1)selective inhibitor without affecting other members of the Forkhead box family. Siomycin A has anti-tumor and promotesapoptosis.

YN251709 Radicicol 12772-57-5

Radicicol is an inhibitor ofHsp90with an IC50 value of 1μM. Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients, leading to proteasomal degradation. Radicicol is an antifungal antibiotic wi...

YN251495 Dryocrassin ABBA 12777-70-7

Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived fromDryopteris crassirhizoma, with antiviral and antibacterial activities. Dryocrassin ABBA exhibits antiviral activity againstH5N1avian influenza virus. ...

YN251108 Mafenide Acetate 13009-99-9

Mafenide Acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.

YN250300 HPi1 13080-21-2

HPi1 is a potent, selective and orally active antimicrobial againstHelicobacter pyloriwith an IC50 of 0.24μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensalsLactobacillu...

YN251439 Betulinaldehyde 13159-28-9

Betulinaldehyde has the inhibition of Saccharomyces sp and alpha-glucosidase. Betulinaldehyde induces apoptosis in mouse B16 2F2 cells. Betulinaldehyde has anti-proliferative activity against mouse +SA mammary epithelial cells.

YN250329 Metronidazole Benzoate 13182-89-3

Metronidazole Benzoate is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.

YN250458 Mequindox 13297-17-1

Mequindox is an antimicrobial agent. Mequindox acts as an inhibitor ofDNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice.

YN250490 Nifurpirinol 13411-16-0

Nifurpirinol (P-7138) is a nitroaromaticantibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent prodrug compared to Metronidazole to trigger cell-ablation in nitroreducta...

YN251191 Dicloxacillin Sodium hydrate 13412-64-1

Dicloxacillin Sodium hydrate (DLX, Dycill, Dynapen, Pathocil), a narrow-spectrum β-Lactam antibiotic of the penicillin class, induces drug-metabolizing CYP enzymes to a clinically relevant extent.

YN250231 Actinonin 13434-13-4

Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced byActinomyces. Actinonin inhibitsaminopeptidase M,aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversiblepeptide deformylase (PDF...

YN251101 Zinc Pyrithione 13463-41-7

Zinc pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.

YN250272 Anhydrotetracycline hydrochlo... 13803-65-1

Anhydrotetracycline hydrochloride, a tetracycline biosynthetic precursor, is a potent competitive broad-spectrum tetracycline destructase enzymes inhibitor. Anhydrotetracycline hydrochloride is an effector for tetracycline controlled gene...

YN251601 Stearyl glycyrrhetinate 13832-70-7

Stearyl glycyrrhetinate, a major component in licorice extract, has a MIC againstS. aureusstrains of more than 256 mg/L. Stearyl glycyrrhetinate hasantibacterialeffects.

YN250116 Azidamfenicol 13838-08-9

Azidamfenicol is a broad-spectrum chloramphenicol-like antibiotic. Azidamfenicol inhibits ribosomal peptidyltransferase (Ki=22 µM).

YN251331 Emetine hydrochloride 14198-59-5

Emetine hydrochloride, derived from the ipecac root, is a potent anti-protozoal and emetic agent. Emetine hydrochloride inhibitsviral polymerases and inhibits Zika and Ebola virus infections. Emetine hydrochloride potently inhibit...

YN251459 Hederacoside C 14216-03-6

Hederacoside C (HDC) is one of the active ingredients in Hedera helix leaf extract (Ivy Ex.) and used to treat respiratory disorders.

YN250992 Prothionamide 14222-60-7

Protionamide is a drug used in the treatment of tuberculosis.

YN251533 Narirutin 14259-46-2

Narirutin, one of the active constituents isolated fromCitrus unshiu, has antioxidant and anti-inflammatory activities. Narirutin is ashikimate kinaseinhibitor with anti-tubercular potency.

YN251237 Furaltadone L-tartrate 14343-71-6

Furaltadone L-tartrate (Altafur L-tartrate), a nitrofuran drug, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci.