YN250760 Dalbavancin hydrochloride 2227366-51-8

Dalbavancin hydrochloride (MDL-63397 hydrochloride) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity againstGram-positive bacteria. Dalbavancin hydrochloride inhibitsStaphylococcus aureus and Bacillus...

YN250362 G907 2244035-16-1

G907 is a selective small-molecule antagonist ofATP-binding cassette (ABC) transporter, MsbA. It inhibits purifiedE. coliMsbA in amphipols with an IC50 of 18nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-boun...

YN250180 Taniborbactam hydrochloride 2244235-49-0

Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrumβ-lactamaseinhibitor with IC50s of 8-530nM. Taniborbactam hydrochloride hasIC50s of 30nM, 32nM, 42nM, 2...

YN250518 N-Acetylmuramic acid-alkyne 2245794-65-2

N-Acetylmuramic acid-alkyne is a derivative of N-acetylmuramic acid (NAM) component of bacterial peptidoglycans. N-Acetylmuramic acid-alkyne incorporates into bacterial peptidoglycans during biosynthesis. N-Acetylmuramic acid-alky...

YN250203 TBAJ-587 2252316-16-6

TBAJ-587, a potentanti-tuberculosisagent, inhibitsM.tbstrain H37Rv growth withMIC90s of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively. TBAJ-587 inhibits hERG channel minimally, attenuates inhibiti...

YN250219 MBX-4132 2286411-30-9

MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.

YN250418 SPR206 acetate 2408422-41-1

SPR206 acetate is a polymyxin analog with antibiotic activity againstGram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s...

YN250448 JH-LPH-33 2414590-04-6

JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolaseLpxHinhibitor. JH-LPH-33 displays outst and ingantibioticactivity with a MIC value of 0.66 μg/mL.

YN250447 JH-LPH-28 2414592-36-0

JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolaseLpxHinhibitor. JH-LPH-28 displays outst and ingantibioticactivity with a MIC value of 0.83 μg/mL.

YN251716 Meleagrin

Meleagrin is a roquefortine C-derived alkaloid produced by fungi of the genusPenicillium and has antimicrobial and anti-proliferative activities. Meleagrin is a class ofFabIinhibitor. Meleagrin is a leadc-Metinhibitory entity use...