YN250270 Durlobactam sodium salt 1467157-21-6

Durlobactam sodium salt (ETX2514) is a broad-spectrumβ-lactamaseinhibitor with IC50s of 4, 14 and 190nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-n...

YN250183 NITD-349 1473450-62-2

NITD-349 is anMmpL3inhibitor that shows highly potent anti-mycobacterial activity withMIC50 of 23nM against virulentMycobacterium tuberculosisH37Rv.

YN251271 Cefalonium hydrate 1486466-27-6

Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .

YN250182 BM635 1493762-74-5

BM635 is aMmpL3inhibitor with outst and ing anti-mycobacterial activity. BM635 has anMIC50 of 0.12μM againstM. tuberculosisH37Rv.

YN250816 TBA-7371 1494675-86-3

TBA-7371 is a potent, noncovalentDprE1inhibitor. TBA-7371 has potent antitubercular activity.

YN250365 Pseudouridimycin 1566586-52-4

Pseudouridimycin (PUM), an antibiotic, is a selective bacterialRNA polymerase (RNAP)inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria.

YN250327 NITD-916 1614262-83-7

NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active and highly lipophilicmycobacterial enoyl reductase InhAinhibitor with an IC50 of 570nM. NITD-916 forms a ternary complex withInhA and NADH to block acces...

YN250031 DprE1-IN-2 1615713-87-5

DprE1-IN-2 (compound 18) is a potentDprE1inhibitor with an IC50 of 28nM. DprE1-IN-2 has antituberculosis effect.

YN250525 Oxazosulfyl 1616678-32-0

Oxazosulfyl is a potent agriculturalfungicide. Oxazosulfyl can be used as an insecticide against major rice pests.

YN250777 Zoliflodacin 1620458-09-4

Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrionebacterial DNA gyrase/topoisomeraseinhibitor. Zoliflodacin has potentin vitroantibacterial activity against Gram-positive and Gram-negative organisms, includingS....

YN250449 LolCDE-IN-1 1639933-78-0

LolCDE-IN-1 is an inhibitor of theLol proteins (LolCDE) complex, with antibacterial activity.

YN250824 Contezolid acefosamil 1807497-11-5

Contezolid acefosamil (MRX-4) is the orally active prodrug of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria...

YN250804 Ribocil-C 1825355-56-3

Ribocil-C is a highly selective inhibitor ofbacterial riboflavin riboswitches.

YN251912 Danofloxacin-d3 1825377-28-3

Danofloxacin-d3 is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against mostGram-negative and Gram-positive...

YN250376 MDRTB-IN-1 1973401-05-6

MDRTB-IN-1 (5aα) is an antibiotic which is againstMycobacterium tuberculosisH37Rv with aMIC90value of 10.5μM.

YN250441 Propargyl-PEG8-acid 2055014-94-1

Propargyl-PEG8-acid is a cleavableADC linkerused in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria.

YN250148 GSK656 2131798-13-3

GSK656 is a potent antitubercular agent, acting as an inhibitor ofMycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2μM.

YN250467 PK150 2165324-62-7

PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitiveS. aureus(MSSA), Met...

YN250805 Ribocil-C (R enantiomer) 2177266-81-6

Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective inhibitor of bacterial riboflavin riboswitches.

YN250137 Polymyxin B nonapeptide TF... 2220175-42-6

Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its abil...