YN250172 Leu-AMS 288591-93-5

Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor ofleucyl-tRNA synthetase(LRS) with an IC50 of 22.34nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation...

YN250090 Reutericyclin 303957-69-9

Reutericyclin (Reutericycline), a unique tetramic acid, is an antibiotic produced by some strains ofLactobacillus reuteri. Reutericyclin (Reutericycline) exhibits a broad inhibitory spectrum includingLactobacillus spp.,Bacillus subti...

YN251830 Flagelin 22 304642-91-9

Flagelin 22 (Flagellin 22), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae.

YN250680 Ridinilazole 308362-25-6

Ridinilazole is a novelantibacterialwith MICs range of 0.06-0.25 µg/mL (MIC90=8 µg/mL) againstC. difficile.

YN250124 Gatifloxacin mesylate 316819-28-0

Gatifloxacin mesylate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinoloneantibioticwith broad-spectrum antibacterial activity. Gatifloxacin mesylate inhibits bacterialtype II topoisomerases(IC50=13.8 μg/ml forS. aureu...

YN250664 Squalamine lactate 320725-47-1

Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.

YN251849 OV-1, sheep 326855-45-2

OV-1, sheep is an alpha-helical antimicrobial ovispirin peptide derived from SMAP29 peptide (sheep), which inhibits several antibiotic-resistant bacterial strains including mucoid and nonmucoid Pseudomonas aeruginosa.

YN250859 Tildipirosin 328898-40-4

Tildipirosin, a long-acting macrolide, has antibiotic activity.

YN250616 AX20017 329221-38-7

AX20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39μM.

YN251586 7-O-Methylaloeresin A 329361-25-3

7-O-Methylaloeresin A is 5-methylchromone glycoside isolated fromCommiphora socotrana(Burseraceae). 7-O-Methylaloeresin A exhibits good activity against multiple drug resistantStaphylococcus aureus(NCTC 11994) and Salmonella...

YN250833 S.pombe lumazine synthase-IN... 331726-35-3

S.pombe lumazine synthase-IN-1 is an inhibitor oflumazine synthaseswith Ki values of 243μM and 9.6μM forSchizosaccharomyces pombe and Mycobacterium tuberculosislumazine synthases, respectively.

YN250844 I2906 331963-29-2

I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis.

YN250356 ABMA 332108-65-3

ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens includingviruses,intracellular bacteria and parasite. ABMA selectively acts at ho...

YN250601 Delafloxacin meglumine 352458-37-8

Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens.

YN250939 Doripenem monohydrate 364622-82-2

Doripenem Hydrate is an ultra-broad-spectrum injectable antibiotic, used to treat complicated intra-abdominal infections and complicated urinary tract infections.

YN251857 Human β-defensin-2 372146-20-8

Human β-defensin-2 (HβD-2) is a small cysteine-rich cationicskin-antimicrobial peptide (SAP)produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and C and ida, bu...

YN251866 rCRAMP (rat) 376364-38-4

rCRAMP (rat) is the rat cathelin-related antimicrobial peptide. rCRAMP (rat) contributes to the antibacterial activity in rat brain peptide/protein extracts. rCRAMP (rat) is a potential key player in the innate immune system ...

YN250593 Ceftaroline fosamil 400827-46-5

Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).

YN250696 Besifloxacin Hydrochloride 405165-61-9

Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.

YN250264 Thiophene-2 420089-51-6

Thiophene-2 (TP2) is a specificpolyketide synthase 13 (Pks13)inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active againstMycobacterium tuberculosiswith a MI...