Fenebrutinib
Cat. No. :YN440393
CAS No. :1434048-34-6
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order@ubiochem.com| Product Name: | Fenebrutinib |
| CAS NO.: | 1434048-34-6 |
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| Molecular Weight: | 664.80 |
| Molecular Formula: | C₃₇H₄₄N₈O₄ |
| SMILES: | O=C1C(NC(C=C2)=NC=C2N3CCN(C4COC4)C[C@@H]3C)=CC(C5=CC=NC(N6C(C7=CC(CC(C)(C)C8)=C8N7CC6)=O)=C5CO)=CN1C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent bruton's tyrosine kinase (Btk) inhibitor with Kis of 0.91nM, 1.6, 1.3, 12.6, and 3.4nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research. |
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